Respiratory and upper limb function as outcome measures in ambulant and non-ambulant subjects with Duchenne...

Respiratory and upper limb function as outcome measures in ambulant and non-ambulant subjects with Duchenne..., Duchenne muscular dystrophy (DMD) is a rare, X-linked neuromuscular disorder with an estimated incidence of approximately 1 in 3.500 to 1 in 5.000 live male births. [1–3] DMD is caused by mutations in the dystrophin gene (DMD) that lead to an absence or near-absence of dystrophin, a protein essential for muscle cell integrity., Duchenne muscular dystrophy (DMD) is a rare, X-linked neuromuscular disorder with an estimated incidence of approximately 1 in 3.500 to 1 in 5.000 live male births. [1–3] DMD is caused by mutations in the dystrophin gene (DMD) that lead to an absence or near-absence of dystrophin, a protein essential for muscle cell integrity. [4] The profound deficiency of dystrophin seen in DMD results in progressive muscle degeneration and loss of function, culminating in premature death, typically by age 30., admin,