PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier...

PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier..., Phosphatidylinositol 3-kinase signaling promotes cell growth and survival and is frequently activated in infiltrative gliomas. Activating mutations in PIK3CA gene are observed in 6–15% of glioblastomas, although ..., Phosphatidylinositol 3-kinase signaling promotes cell growth and survival and is frequently activated in infiltrative gliomas. Activating mutations in PIK3CA gene are observed in 6–15% of glioblastomas, although ..., admin,