Management of the dentoalveolar effects of tongue hypertrophy in patients with Duchenne muscular dystrophy: a...

Management of the dentoalveolar effects of tongue hypertrophy in patients with Duchenne muscular dystrophy: a..., Duchenne muscular dystrophy (DMD), is a life-limiting X-linked recessive neuromuscular disorder primarily affecting boys, with an incidence of 1 in 3,500-5,000 live male births, making it the most prevalent muscular dystrophy of childhood in boys [1]., Duchenne muscular dystrophy (DMD), is a life-limiting X-linked recessive neuromuscular disorder primarily affecting boys, with an incidence of 1 in 3,500-5,000 live male births, making it the most prevalent muscular dystrophy of childhood in boys [1]. DMD is caused by mutations in the dystrophin gene, leading in most cases to complete absence of the dystrophin protein, a cytoskeleton protein critical for the stability and normal function of the myofibers. DMD results in progressive muscle degeneration that manifests generally between three and six years of age, leading to loss of independent ambulation in the second decade, pulmonary and cardiac complications, and ultimately premature death [2]., admin,