Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal...

Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal..., Lahiri and Bevan demonstrate that dopaminergic transmission powerfully enhances the intrinsic excitability of D1 receptor-expressing striatal projection neurons in a state-independent manner. Dynamic biophysical changes argue that different ion channel mechanisms may underlie the initial and long-lasting phases of modulation., Lahiri and Bevan demonstrate that dopaminergic transmission powerfully enhances the intrinsic excitability of D1 receptor-expressing striatal projection neurons in a state-independent manner. Dynamic biophysical changes argue that different ion channel mechanisms may underlie the initial and long-lasting phases of modulation., admin,