Quantification of Visible Virchow–Robin Spaces for Detecting the Functional Status of the Glymphatic System...

Quantification of Visible Virchow–Robin Spaces for Detecting the Functional Status of the Glymphatic System..., As part of the brain’s immune system, the cerebral glymphatic system plays an important role in waste clearance from the brain [1,2]. Cerebral perivascular Virchow-Robin spaces (VRS) are functional networks of the cerebral glymphatic system surrounding the perforating arterioles and venules in the brain parenchyma [1,2]., As part of the brain’s immune system, the cerebral glymphatic system plays an important role in waste clearance from the brain [1,2]. Cerebral perivascular Virchow-Robin spaces (VRS) are functional networks of the cerebral glymphatic system surrounding the perforating arterioles and venules in the brain parenchyma [1,2]. They are always located between the endothelial basement membrane and the basement membrane of the glia limitans [3]. Additionally, the VRS are responsible for immune surveillance and drainage of soluble proteins and metabolic waste products from the brain, within the overarching glymphatic system [4,5]., admin,