Surgical Treatment of Nonlesional Neocortical Epilepsy. Long-term Longitudinal Study


Dong Wook Kim, Sang Kun Lee, Hye-Jin Moon, Ki-Young Jung, Kon Chu, Chun-Ki Chung,

JAMA Neurol. Published online January 3, 2017. doi:10.1001/jamaneurol.2016.4439



What are the long-term surgical outcomes and the possible prognostic factors in patients with nonlesional neocortical epilepsy?

In a long-term study that included 109 patients, nearly 60% of patients with nonlesional neocortical epilepsy achieved long-term freedom from seizure. Several factors, including localizing patterns in functional neuroimaging, concordant results in presurgical diagnostic evaluations, and the presence of aura, were associated favorable surgical outcome.
Patients with nonlesional neocortical epilepsy can be good surgical candidates, and the presence of predictors of favorable surgical outcome would help select optimal candidates for surgical treatment.

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